Not filler. Not just hydration. A regenerative polynucleotide treatment in London, from my Fulham SW6 studio, repairing your skin at a cellular level to improve strength, texture, and overall skin quality over time.
Polynucleotides are designed to improve skin quality from within, rather than change your face.
They work by stimulating repair, hydration, and collagen production over time.
Send me a photo on WhatsApp and I will tell you honestly what to expect before you book.
Usually responds within a few hours
Polynucleotides are a regenerative skin treatment with several areas of focus. Explore by what matters most to you. Results build gradually over a course, and your plan is always individualised.
Polynucleotides support hydration and overall skin quality for a fresher, more radiant look.
Best for
PDRN helps skin attract and hold moisture from within, not just on the surface.
Best for
This improves the quality of your skin rather than adding volume like a traditional filler.
Best for
Real client results. No filters, no editing. Just healthier skin.
These photographs show a real client immediately before treatment (left) and immediately afterwards (right). Temporary redness is a normal response following polynucleotide injections and typically settles within 24 to 48 hours. Improvements in skin quality, hydration and firmness develop gradually over the following weeks as the skin naturally regenerates collagen and elastin.
Individual results vary. Photographs are shared with client consent.
20-30 minutes per session
Minimal. Slight swelling for 24-48 hours
Minimal. Numbing cream available
3 sessions, 2-4 weeks apart
Polynucleotides Skin Boost (Vitaran)
A regenerative polynucleotide derived from purified salmon DNA. Best for prevention, hydration, glow and under-eye rejuvenation. Course of 3 recommended, 3 weeks apart.
Polynucleotides Advanced Skin Repair (Plenhyage XL Strong)
Higher-concentration (2.5% HMW) polynucleotide for deeper tissue repair. Best for acne scarring, sun damage and advanced ageing. Excellent primer before HIFU or Microneedling with Exosomes.
Which is right for me?
Vitaran Skin Boost if you want prevention, maintenance, hydration, glow or under-eye rejuvenation.
Plenhyage XL Strong if you want deeper repair for acne scarring, sun damage, skin laxity, or a primer before HIFU or Microneedling.
Appointments are limited each week to maintain treatment quality.
Included at no additional cost with qualifying skin treatments.
All regenerative skin treatments at Georgina Sookias Aesthetics include complimentary professional Red Light Therapy.
Our professional system combines 630nm and 660nm red light with 810nm, 830nm and 850nm near infrared wavelengths. These wavelengths have been widely studied for their ability to support skin health, cellular energy production and collagen synthesis.
As part of our regenerative approach to skin health, we include professional Red Light Therapy after qualifying treatments to support the skin during the recovery phase and enhance the overall treatment experience at no additional cost.
This is provided complimentary with all qualifying skin treatments as part of our regenerative approach to skin health.
Learn more about red light therapyThis is not an instant treatment. It builds.
Skin looks brighter and more refreshed, with a hydrated, healthier glow.
Polynucleotides (PDRN) begin attracting and holding moisture while signalling fibroblasts to wake up.
An early freshness rather than the full result. This is the beginning of the build.
Anyone with dull, tired or dehydrated-looking skin wanting an early lift.
Texture smooths, dark circles lighten and fine lines start to soften.
Fibroblast activity increases, supporting new collagen and elastin in the deeper skin.
Gradual, visible improvement across a course rather than an overnight change.
Clients addressing under-eye quality, texture and early fine lines.
Skin looks significantly healthier, firmer and more youthful.
Collagen and elastin remodelling reaches its peak after a completed course.
This is where most clients see their best result, with a full course of sessions.
Clients who have completed a course and want maximum skin-quality improvement.
Results hold, with skin that looks and feels more resilient over time.
Repeated treatments build a stronger, better-supported skin foundation.
Results are maintained with periodic treatments, not a one-off fix.
Anyone investing in long-term skin health rather than a quick fix.
Ready to rebuild your skin from within?
Book your consultationA client in her early 40s came in confused. She had been quoted nearly two thousand pounds for filler at another clinic and felt pushed into it. Her real issue was not volume loss, it was tired, depleted skin. We did a course of polynucleotides across three sessions. She later told me it was the first time anyone had explained her skin to her, instead of trying to sell her something.
"I came in unsure and she guided me honestly. My skin looks so much healthier now."
"After one session my skin felt completely different. Calm, professional, transformative."
"After a course my skin looks completely different. Brighter, smoother, healthier."
"A game changer for my acne scarring. She really understands skin on a deeper level."
Naturally occurring DNA fragments that repair and regenerate damaged skin at a cellular level. Unlike Profhilo which hydrates, polynucleotides actually rebuild your skin from within. Combines brilliantly with HIFU for enhanced lifting.
This is why polynucleotides don't just improve how your skin looks. They improve how it functions.
Want to know if polynucleotides suit your skin?
Get personalised advicePurified DNA fragments are injected beneath the skin. They activate your body's repair systems at a cellular level, stimulating fibroblasts, repairing DNA damage, and triggering genuine tissue regeneration. Some clients also explore exosomes vs polynucleotides when considering regenerative options.
Stimulate fibroblasts to produce collagen, elastin, and hyaluronic acid
Fix cellular DNA damage from UV exposure and environmental stress
Promote healthy new tissue growth and remodelling
Neutralize free radicals and reduce chronic inflammation
Cellular repair, under-eyes, skin quality
Healthier, firmer, more youthful skin
Minimal. Slight swelling for 24-48 hours
3 sessions, 2-4 weeks apart
6-12 months
Profhilo hydrates and firms. Polynucleotides go deeper, repairing tissue and rebuilding skin at a cellular level. Different jobs, and they work brilliantly together. Read the full polynucleotides vs Profhilo comparison.
Fillers add volume. Polynucleotides improve the actual quality of your tissue. For under eyes especially, polynucleotides give more natural results without the risk of filler migration. See our full polynucleotides vs fillers breakdown.
Not sure which treatment is right for you?
Start your skin planView real results on our Results gallery or see treatment pricing.
Most clients I see for polynucleotides aren't trying to change how they look.
They just feel like their skin doesn't reflect how they feel anymore.
It can feel dull, dehydrated, or slightly crepey.
They don't want filler. They don't want anything obvious.
They just want their skin to look healthy again. That's exactly where polynucleotides work best.
They don't want compliments on a treatment, they just want to hear they look well.
If lifting is also a concern, this is often combined with HIFU for best results.
Send me a photo and I will tell you honestly what I would recommend.
Send me a photo on WhatsApp and I will tell you honestly what to expect before you book.
Usually responds within a few hours
Polynucleotides are not a quick fix.
They work gradually by improving skin quality over time.
Results build over a series of treatments, and continue improving as your skin regenerates.
This is why the results look natural and long-lasting.
Polynucleotides work best for improving skin quality. If you are looking for lifting or volume, I will always guide you towards the right treatment instead.
If you're not sure whether polynucleotides are right for you, send me a photo on WhatsApp and I'll tell you honestly if it's right for you, and what results you can realistically expect.
No pressure. Just honest advice.
Send me a photo on WhatsApp and I will tell you honestly what to expect before you book.
Usually responds within a few hours
Polynucleotides are not just about the product used.
They depend on correct placement, technique, and understanding of skin structure.
A personalised approach is what creates visible improvement while keeping results natural.
If your skin feels like it's changing, thinning, or not looking how it used to... this is where we fix it properly.
Polynucleotides are often used as a foundation for other treatments.
Once skin quality is improved, treatments like HIFU can be used to lift and tighten more effectively.
This approach focuses on regeneration first, then correction.
Based in Fulham SW6, serving clients across Chelsea, Putney, Barnes, Wimbledon, Battersea, and Knightsbridge.
Read our detailed polynucleotides cost guide for London pricing.
Send me a photo on WhatsApp and I will tell you honestly what to expect before you book.
Usually responds within a few hours
Read our Pre-Holiday Beauty Prep Guide for the best timing.
Most of our polynucleotides clients travel in from neighbouring boroughs. If you are closer to one of the areas below, the page for your area covers travel time, getting here and what to expect.
Polynucleotides near Chelsea
15 minutes from our Fulham clinic
Polynucleotides near Battersea
10 minutes from our Fulham clinic
Polynucleotides near Knightsbridge
20 minutes from our Fulham clinic
Polynucleotides near Putney
20 minutes from our Fulham clinic
Polynucleotides near Wandsworth
15 minutes from our Fulham clinic
Polynucleotides near Clapham
20 minutes from our Fulham clinic
Polynucleotides near Wimbledon
25 minutes from our Fulham clinic
Polynucleotides work at the level your skin actually needs. Not surface-level. Not temporary. Real repair, real results.